A scientific lecture entitled, Silymarin in
Chronic Viral Hepatitis, the Evidence behind the Medicine was
presented during the joint annual convention of the Philippine
Society of Gastroenterology, the Philippine Society of Digestive
Endoscopy, and the Hepatology Society of the Philippines.
The lecture was delivered by Dr. Diana
Alcantara-Payawal of the Philippine Society of Gastroenterology,
Hepatology Society of the Philippines, Cardinal Santos Medical
Center and UST, and Dr. Anuchit Chutaputti, of the
Phramongkutklao Hospital in Bangkok, Thailand, last Monday at
the EDSA Shangri-La hotel in Mandaluyong. Also known as the
Philippine Digestive Health Week 2008, the annual event was held
from March 10-12.
" Chronic hepatitis B consists of persistent
liver infection and inflammation that lingers long after the
primary symptoms of the disease have disappeared. Chronic
hepatitis B is the leading cause of liver cancer in the
Philippines."Hepatitis B virus is most commonly transmitted
through blood-to-blood contact," says Dr. Payawal.
Silymarin is known to have been used for
centuries to treat liver ailments. Recent findings have shown
that it has the ability to block fibrosis, a process that
contributes to the eventual development of cirrhosis in persons
with inflammatory liver conditions secondary to viral hepatitis
B or C. This action makes milk thistle extract potentially
attractive as a supportive treatment for the
condition-particularly for those that have not responded to
standard drug therapy. T
Milk thistle, sometimes called silymarin is actually a
mixture of the herb’s active components, including silybinin
(also called silibinin or silybin). However, not all silymarins
are made the same. The amount of silybinin in each drug differs
thus its effectiveness. Dissolution properties of silymarin
extracts vary. Results of a dissolution study conducted proved
Legalon 140, a clinically proved to be highly bioavailable by
releasing as much as 90 percent of the active component
silybinin, within 45 minutes as compared to another brand which
has very minimal release of only 10 percent within the same
period. It is also very well-tolerated.